Supplements, Research, AML Herbal Regimen
Plant Synergisms: (Leveraging a Lot with a Little)
Would you try to open a locked doorknob with a massive pipewrench?
You could crank the knob breaking a big hole in the door to gain entry.
Wouldn't it be easier to use a key, or at least find the right combination of tiny tumblers with a lock pick?
Cancer treatment could be like that. Rather than continuing to bludgeon the body with massive cellular DNA damage, if we
employ the right combinations of phytochemicals - seesawing ROS levels, epigenetic compensation, and hormetic stimulation
then we open the door with a minimum of energy ...using brains instead of brawn.
A drawback with many nutritional supplements, is they follow the lead of traditional drug models:
"achieve maximum dosage with minimum acceptable toxicity"
. "EGCG" supplements are advertised instead of whole plant Green Tea.
Ellagic Acid instead of focusing on the best pomegranate, cranberry, etc.
I am not denying the need for intense therapy
, especially in out-of-control
situations. However, I am gathering here on this page, links to studies that highlight the synergistic effects of compounds present
at effective levels in whole foods / whole plants. In many cases we lose benefits when we distort the ratios present
in the original foods. Those plants were designed better the way they were ...instead of "maxing out" a specific component
it may be more valuable to obtain lower concentrations of a pure plant supply and coordinate/alternate the sequence of usage properly
with other supplements and
with rhythms of fasting, growth, excercise, and recovery.
Do not omit proper rest and laughter - I could gather scientific evidence that for some "resistant cancers" fasting, followed by
drinking green and burdock tea while munching on raw apples and broccoli sprinkled with curcumin, playing with children, and snuggling with a pet could
have greater success than $20,000 of chemo infusions.
Low concentrations of quercetin and ellagic acid synergistically influence proliferation, cytotoxicity and apoptosis in MOLT-4 human leukemia cells
Mechanisms of combined action of different chemopreventive dietary compounds: a review
Ellagic acid and quercetin interact synergistically with resveratrol in the induction of apoptosis and cause transient cell cycle arrest in human leukemia cells
Mediterranean diet health benefits may be due to a synergistic combination of phytochemicals and fatty-acids
Food bioactives, apoptosis, and cancer
"...accumulating evidence supports the notion that a combination of food bioactives is more effective than treatment with a single dietary compound
Total cranberry extract versus its phytochemical constituents: antiproliferative and synergistic effects against human tumor cell lines
In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagic acid and a total pomegranate tannin extract are enhanced in combination with other polyphenols as found in pomegranate juice
Health benefits of fruit and vegetables are from additive and synergistic combinations of phytochemicals
Potential synergy of phytochemicals in cancer prevention: mechanism of action.
Why Whole Mushrooms or Mushroom Extracts May Be More Beneficial Than Isolated Constituents
Potential synergism of natural products in the treatment of cancer
Probiotic (Gut Flora) Synergisms:
The potent in vitro antioxidant ellagitannins from pomegranate juice are metabolised into bioavailable but poor antioxidant hydroxy-6H-dibenzopyran-6-one derivatives by the colonic microflora of healthy humans
Chemopreventive effects of natural dietary compounds on cancer development.
Hormones + AntiOxidents = Differentiation:
Differentiation of human myeloid leukemia cells by plant redifferentiation-inducing hormones
Fasting ...Phytochemicals ...Hormetic Response
Dietary factors, hormesis and health
Cellular stress response: a novel target for chemoprevention and nutritional neuroprotection in aging, neurodegenerative disorders and longevity