Supplements, Research, AML Herbal Regimen
Reishi Mushrooms / Ganoderma lucidum
Components: triterpenoids, polysaccharides, lucidenic acid
Effects: Apoptosis, Differentiation, Phagocytosis, Cytokine/Immunoglobulin Production
The anti-tumor effect of Ganoderma lucidum is mediated by cytokines released from activated macrophages and T lymphocytes.
The Immunomodulating Effects of Ganoderma lucidum (Curt.: Fr.) P. Karst. (Ling Zhi, Reishi Mushroom) (Aphyllophoromycetideae)
Ganoderma lucidum suppresses motility of highly invasive breast and prostate cancer cells.
Cancer Prevention and Treatment by Ganoderma, a Mushroom with Medicinal Properties
Ganoderma Lucidum(Reishi) in Cancer Treatment
Ganoderma lucidum suppresses growth of breast cancer cells through the inhibition of Akt/NF-kappaB signaling.
Ganoderma lucidum inhibits proliferation and induces apoptosis in human prostate cancer cells PC-3.
Immune receptors for polysaccharides from Ganoderma lucidum
Ganoderma lucidum causes apoptosis in leukemia, lymphoma and multiple myeloma cells.
Reishi polysaccharides induce immunoglobulin production through the TLR4/TLR2-mediated induction of transcription factor Blimp-1
Ganoderma lucidum polysaccharides in human monocytic leukemia cells: from gene expression to network construction.
Ganoderma lucidum and its pharmaceutically active compounds.
Enhancement of radiation response with combined Ganoderma lucidum and Duchesnea chrysantha extracts in human leukemia HL-60 cells.
Lucidenic acid B induces apoptosis in human leukemia cells via a mitochondria-mediated pathway.
Phagocytosis and Chemotaxis
Polysaccharide purified from Ganoderma lucidum inhibits spontaneous and Fas-mediated apoptosis in human neutrophils through activation of the phosphatidylinositol 3 kinase/Akt signaling pathway
Signaling mechanisms of enhanced neutrophil phagocytosis and chemotaxis by the polysaccharide purified from Ganoderma lucidu
Ganoderma lucidum polysaccharides enhance the function of immunological effector cells in immunosuppressed mice
Phagocytosis and antigen presentation in dendritic cells
Roles of PI3K in neutrophil function
Immunotherapy with Dendritic cells:
The effect of Ganoderma lucidum on induction of differentiation in leukemic U937 cells.
Regulatory effects of Ganoderma lucidum polysaccharides on Cytotoxicity and mechanism of T-lymphocytes induced by dendritic cells (DC) in vitro
Polysaccharide purified from Ganoderma lucidum induced activation and maturation of human monocyte-derived dendritic cells by the NF-kappaB and p38 mitogen-activated protein kinase pathways.
Ganoderma lucidum polysaccharides can induce human monocytic leukemia cells into dendritic cells with immuno-stimulatory function.
Immunotherapy with dendritic cells for cancer
Experimental and clinical studies on inhibitory effect of ganoderma lucidum on platelet aggregation
Sloan Kettering: Healthcare Professional Review
Peking University: Cellular and molecular mechanisms of immuno-modulation by Ganoderma lucidum