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Supplements, Research, AML Herbal Regimen

Peer reviewed journal papers preferred (PubMed) see: Google Scholar
Other Resources: NCCAM Clinical Trial Directory, Complimentary Medicine Search
Evidence Based CAM, Oregon State University, Sloan Kettering, Creighton University, NCCAM Herbs, HerbMed, Sigma-Aldrich

Apoptosis, Review, Epigenetics, ROS Therapy, Blood-Brain, Cell Paths, Synergisms
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Milk Thistle (Silymarin, Silibinin, Silipide)
Cancer Treatment and Milk Thistle
2003 Jun Milk thistle: is there a role for its use as an adjunct therapy in patients with cancer?
2007 Jun Clinical applications of Silybum marianum in oncology.
2007 Jun Future directions for research on Silybum marianum for cancer patients.
2008 May Multitargeted therapy of cancer by silymarin.

Milk Thistle for Prostate Cancer:
2002 Nov Antiproliferative and apoptotic effects of silibinin in rat prostate cancer cells.
2004 May Inhibition of telomerase activity and secretion of prostate specific antigen by silibinin in prostate cancer cells.
2007 Dev Silibinin suppresses in vivo growth of human prostate carcinoma PC-3 tumor xenograft.
2008 Apr Evaluation of the cancer chemopreventive efficacy of silibinin in genetic mouse models of prostate and intestinal carcinogenesis: relationship with silibinin levels.

Clinical Trials of Milk Thistle:
2007 Jun Review of clinical trials evaluating safety and efficacy of milk thistle (Silybum marianum [L.] Gaertn.).
2008 Feb An updated systematic review with meta-analysis for the clinical evidence of silymarin.

Milk Thistle and the Liver:
2001 Mar Milk thistle and the treatment of hepatitis.
2002 Oct Milk thistle for the treatment of liver disease: a systematic review and meta-analysis.
2005 Apr Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases.
2006 Jun The Use of Selected Nutrition Supplements and Complementary and Alternative Medicine in Liver Disease
2007 Jun Advances in the use of milk thistle (Silybum marianum)
2008 Jul Effects of silymarin on the resolution of liver fibrosis induced by carbon tetrachloride in rats.

Caution - Milk Thistle "Estrogen Like" activity enhances breast cancer:
2006 Sep Enhancement of mammary carcinogenesis in two rodent models by silymarin dietary supplements.

Other Milk Thistle Research:
#2 Mayo Clinic
#3 Creighton University
#4 Sloan Kettering