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Jaymun's Journey
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Supplements, Research, Herbal Regimen


Peer reviewed journal research preferred (PubMed) see: Google Scholar
Other Resources: NCCAM Clinical Trial Directory, Complimentary Medicine Search
Evidence Based CAM, Oregon State University, Sloan Kettering, Creighton University, NCCAM Herbs, HerbMed, Sigma-Aldrich


Purpose, Method, Dose Log
Green Tea (Catechins / EGCG / Polyphenol)
Leukemia:
1997 Effect of (-)-epigallocatechin gallate on leukemic blast cells from patients with acute myeloblastic leukemia.
1998 Growth inhibition of leukemic cells by (-)-epigallocatechin gallate, the main constituent of green tea.
2001 Jun Green tea polyphenol epigallocatechin inhibits DNA replication and consequently induces leukemia cell apoptosis.
2004 Mar VEGF receptor phosphorylation status and apoptosis is modulated by a green tea component, epigallocatechin-3-gallate (EGCG), in B-cell chronic lymphocytic leukemia.
2005 Mar Catechin, a green tea component, rapidly induces apoptosis of myeloid leukemic cells via modulation of reactive oxygen species production in vitro and inhibits tumor growth in vivo.
2006 Oct Induction of apoptosis via the modulation of reactive oxygen species (ROS) production in the treatment of myeloid leukemia.

Cancer:

1999 Mar Green tea polyphenols and cancer: biologic mechanisms and practical implications.
2003 Mar Green tea polyphenol targets the mitochondria in tumor cells inducing caspase 3-dependent apoptosis.
2005 Aug Green tea component, catechin, induces apoptosis of human malignant B cells via production of reactive oxygen species.
2006 Dec Green tea polyphenol epigallocatechin-3-gallate suppresses rat hepatic stellate cell invasion by inhibition of MMP-2 expression and its activation
2007 May A Novel Prodrug of the Green Tea Polyphenol (–)-Epigallocatechin-3-Gallate as a Potential Anticancer Agent
2007 Jul Effects of dietary flavonoids on apoptotic pathways related to cancer chemoprevention
2007 Apr (-)-Epigallocatechin gallate suppresses endothelin-1-induced interleukin-6 synthesis in osteoblasts: Inhibition of p44/p42 MAP kinase activation

Crossing the Blood-Brain Barrier:
2002 Dec Uptake and metabolism of epicatechin and its access to the brain after oral ingestion
2006 Apr Long-Term Administration of Green Tea Catechins Improves Spatial Cognition Learning Ability in Rats1

Skin:
2001 Feb Green tea polyphenol (–)-epigallocatechin-3-gallate treatment of human skin inhibits ultraviolet radiation-induced oxidative stress
2005 Jun Green tea and the skin

Inflamation:
1998 Jul Green Tea Polyphenols Block Endotoxin-Induced Tumor Necrosis Factor-Production and Lethality in a Murine Model

Liver:
2006 Oct Ameliorate Liver Fibrosis
2004 Nov Effects of tea polyphenols on hepatic fibrosis in rats with alcoholic liver disease.
2005 Jun Epigallocatechin-3-gallate, a green-tea polyphenol, suppresses Rho signaling in TWNT-4 human hepatic stellate cells
2007 Dec Green tea polyphenol epigallocatechin-3-gallate inhibits oxidative damage and preventive effects on carbon tetrachloride–induced hepatic fibrosis
2006 May The antifibrogenic effect of (-)-epigallocatechin gallate results from the induction of de novo synthesis of glutathione in passaged rat hepatic stellate cells

Heart:
EGCG inhibits cardiomyocyte apoptosis in pressure overload-induced cardiac hypertrophy and protects cardiomyocytes from oxidative stress in rats

Platelets:
Complex effects of different green tea catechins on human platelets

Fat cells (adipocytes):
#1 Green tea polyphenol epigallocatechin gallate inhibits adipogenesis and induces apoptosis in 3T3-L1 adipocytes.
#2 Inhibitory effect of (-)-epigallocatechin-3-gallate on lipid accumulation of 3T3-L1 cells
#3 The apoptotic effect of green tea (-)-epigallocatechin gallate on 3T3-L1 preadipocytes depends on the Cdk2 pathway
#4 Epigallocatechin gallate-induced apoptosis does not affect adipocyte conversion of preadipocytes.

Breast Cancer:
Green tea polyphenols and its constituent epigallocatechin gallate inhibits proliferation of human breast cancer cells in vitro and in vivo.

Benefits vs. Risks (Rutgers):
Possible Controversy over Dietary Polyphenols: Benefits vs Risks

Other Research:
#1 Sloan Kettering
#2 Thorne Research
#3 NCCAM Herbs
#4 BC Cancer

Standard Supply (to match dose regimen): AZ, NSP

Med Summary

Med Data:
  BM-RPIC -6/6
  Labs -7/7
  H Labs -7/11
  C Labs -7/11
  H Labs -7/16
  C Labs -7/16
  Head CT 7/18
  H Labs -7/21
  C Labs -7/21
  Head CT -7/21
  H Labs -7/26
  C Labs -7/26
  Head CT -7/28
  H Labs -8/04
  C Labs -8/04
  Head CT -8/04
  H Labs -8/18
  C Labs -8/18
  H Labs -9/04
  C Labs -9/04
  VNTR -9/04

Supplements:
  Purpose/Goals
  Methods
  Dosage Log
    Feverfew
    Tumeric
    Rieshi Mush.
    Una da Gato
    Onions
    Apples
    Green Tea
    Astragalus
    Milk Thistle
    Synbiotics
    Vitamin K2
    Vitamin E
    Fish Oil
    Parsley
    Burdock
    Echinacea
    Garlic
    Mangosteen
    Pau d'Arco

Work in Progress:
    Aloe Vera
    Soy
    Mistletoe
    Boswellia
    Vitamin D3
    Honokiol
    Pomegranate
    Goji
    Thunder Of God
    Others

Relapse Ramblings

Acute Myeloid
Leukemia


Infant Nutrition

Alternative
Therapy?