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Supplements, Research, AML Herbal Regimen

Peer reviewed journal papers preferred (PubMed) see: Google Scholar
Other Resources: NCCAM Clinical Trial Directory, Complimentary Medicine Search
Evidence Based CAM, Oregon State University, Sloan Kettering, Creighton University, NCCAM Herbs, HerbMed, Sigma-Aldrich

Apoptosis, Review, Epigenetics, ROS Therapy, Blood-Brain, Cell Paths, Synergisms
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Garlic (allicin, ajoene)

1998 Mar Ajoene, a Compound of Garlic, Induces Apoptosis in Human Promyeloleukemic Cells, Accompanied by Generation of Reactive Oxygen Species and Activation of Nuclear Factor B
(Do NOT use N-Acetyl Cysteine first)
2001 Sep Ajoene, a garlic-derived natural compound, enhances chemotherapy-induced apoptosis in human myeloid leukaemia CD34-positive resistant cells.
2004 Jul Ajoene (natural garlic compound): a new anti-leukaemia agent for AML therapy.
Garlic compounds selectively kill childhood pre-B acute lymphoblastic leukemia cells in vitro without reducint T-cell function:Potential therapeutic use in the treatment of ALL

Cancer Therapy:
2008 Apr Cancer chemoprevention by garlic and its organosulfur compounds-panacea or promise?
2008 May Bioactive food components and cancer risk reduction

2005 Sep Diallyl trisulfide, a constituent of processed garlic, inactivates Akt to trigger mitochondrial translocation of BAD and caspase-mediated apoptosis in human prostate cancer cells
Cancer Research: Antiproliferative Effects of S-Allylmercaptocysteine on Colon Cancer Cells When Tested Alone or in Combination with Sulindac Sulfide
Cancer Research: Induction of Apoptosis by the Garlic-Derived Compound S-Allylmercaptocysteine (SAMC) Is Associated with Microtubule Depolymerization and c-Jun NH2-Terminal Kinase 1 Activation
Carcinogenesis: Antitumor activity of Z-ajoene, a natural compound purified from garlic: antimitotic and microtubule-interaction properties
Garlic "Lectin": A garlic lectin exerted an antitumor activity and induced apoptosis in human tumor cells
"Allicin" AntiCancer: Allicin (from garlic) induces caspase-mediated apoptosis in cancer cells
Various Cancers: The cytotoxic effect of ajoene, a natural product from garlic, investigated with different cell lines.
"How" it works: Glutathione-Related Systems and Modulation of Extracellular Signal–Regulated Kinases Are Involved in the Resistance of AGS Adenocarcinoma Gastric Cells to Diallyl Disulfide–Induced Apoptosis
Protects Intestines against Methotrexate: Aged Garlic Extract Protects against Methotrexate-Induced Apoptotic Cell Injury of IEC-6 Cells

Infection Fighting:
Treats MSRA: Antibacterial activity of a new, stable, aqueous extract of allicin against methicillin-resistant Staphylococcus aureus.
Antifungal: [Ajoene the main active compound of garlic (Allium sativum): a new antifungal agent]
Antifungal: Inhibition of growth of the dimorphic fungus Paracoccidioides brasiliensis by ajoene
"Allicin" AntiCancer: Allicin, a major component of garlic, inhibits apoptosis of macrophage in a depleted nutritional state.
Other Research:
Oregon State University: Linus Pauling Institute