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Supplements, Research, AML Herbal Regimen

Peer reviewed journal papers preferred (PubMed) see: Google Scholar
Other Resources: NCCAM Clinical Trial Directory, Complimentary Medicine Search
Evidence Based CAM, Oregon State University, Sloan Kettering, Creighton University, NCCAM Herbs, HerbMed, Sigma-Aldrich

Apoptosis, Review, Epigenetics, ROS Therapy, Blood-Brain, Cell Paths, Synergisms
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Astragalus (adjunctive Cancer treatment?)
2006 Jan Astragalus-Based Chinese Herbs and Platinum-Based Chemotherapy for Advanced Non–Small-Cell Lung Cancer: Meta-Analysis of Randomized Trials
2007 Oct [Effect of Astragalus polysaccharide on pancreatic cell mass in type 1 diabetic mice]
2007 Jun Astragalus saponins induce growth inhibition and apoptosis in human colon cancer cells and tumor xenograft.
2007 July In vitro and in vivo anti-tumor effects of Astragalus membranaceus
1983 Preliminary observations on the effects of the Chinese medicinal herbs Astragalus membranaceus and Ligustrum lucidum on lymphocyte blastogenic responses
1988 Mar Immunotherapy with Chinese medicinal herbs. I. Immune restoration of local xenogeneic graft-versus-host reaction in cancer patients by fractionated Astragalus membranaceus in vitro

Modulating Chemo/Recovery:
1992 Nov Shi-quan-da-bu-tang (ten significant tonic decoction), SQT. A potent Chinese biological response modifier in cancer immunotherapy, potentiation and detoxification of anticancer drugs.
1995 Aug [Treatment of leucopenia with pure Astragalus preparation--an analysis of 115 leucopenic cases]
1998 Mar Immunotherapy with Chinese medicinal herbs. II. Reversal of cyclophosphamide-induced immune suppression by administration of fractionated Astragalus membranaceus in vivo.
2001 Dec Cycloartane saponins from Astragalus peregrinus as modulators of lymphocyte proliferation.
2002 Nov Cycloartane and oleanane saponins from egyptian astragalus spp. as modulators of lymphocyte proliferation.
2005 Jan Chinese medical herbs for chemotherapy side effects in colorectal cancer patients.

Blood-Brain Barrier:
2009 Mar Astragaloside IV attenuates cerebral ischemia-reperfusion-induced increase in permeability of the blood-brain barrier in rats

2007 June Protective effects of emodin and astragalus polysaccharides on chronic hepatic injury in rats
2005 Oct Effect of Astragalus complanatus flavonoid on anti-liver fibrosis in rats.

2002 Oct [Adjustment effect of Radix Astragalus and Radix Angelicae sinensis on TNF-alpha and bFGF on renal injury induced by ischemia reperfusion in rabbit]
2003 Apr [Experimental study on effect of Astragalus extractum on canine isolated kidney during hypothermia perfusion and preservation]
2004 Protective Effects of Astragalus Saponin I on Early Stage of Diabetic Nephropathy in Rats

2007 Mar Effect of astragaloside on cardiomyocyte apoptosis in murine coxsackievirus B3 myocarditis.
2008 Mar Astragalus prevents diabetic rats from developing cardiomyopathy by downregulating angiotensin II type2 receptors expression
2005 Sep [Effect of Astragalus injection on plasma levels of apoptosis-related factors in aged patients with chronic heart failure.]

2007 Jul [Effect of Astragalus membranacaus injection on activity of intestinal mucosal mast cells and inflammatory response after hemorrahagic shock-reperfusion in rats]

2006 Feb Astragaloside IV exerts antiviral effects against coxsackievirus B3 by upregulating interferon-gamma.

2000 Jun Inhibitory effects of astragali radix, crude drug in Oriental medicines on lipid peroxidation and protein oxidative modification of mouse brain homogenate by copper.

How it works: (increases IL-1beta and TNF-alpha)
2000 Jul Immunostimulatory effects of cycloartane-type triterpene glycosides from astragalus species.
2005 Jan Effects of triterpene saponins from Astragalus species on in vitro cytokine release.

Other Research:
Thorne Research
M.D. Anderson
American Cancer Society
Sloan Kettering