Supplements, Research, AML Herbal Regimen
(procyanidins, catechin, epicatechin, chlorogenic acid, phloridzin, quercetin conjugates)
Antitumor activities of apple extracts
Apple procyanidins induce tumor cell apoptosis through mitochondrial pathway activation of caspase-3
Leukemia - synergy with ellagic acid and resveratrol (red raspberries, cranberries, and muscadine grapes)
Low Concentrations of Quercetin and Ellagic Acid Synergistically Influence Proliferation, Cytotoxicity and Apoptosis in MOLT-4 Human Leukemia Cells–
Chemopreventive properties of apple procyanidins on human colon cancer-derived metastatic SW620 cells and in a rat model of colon carcinogenesis
Dietary flavonoids and the risk of lung cancer and other malignant neoplasms.
Intake of Flavonoids and Lung Cancer
Nutrition: Antioxidant activity of fresh apples
Antioxidant activity of apple peels.
Antioxidant and Antiproliferative Activities of Common Fruits
Apple Phenolics Protect in Vitro Oxidative Stress-induced Neuronal Cell Death
How it works:
Effect of Apple Extracts on NF-B Activation in Human Umbilical Vein Endothelial Cells
Effect of 2alpha-Hydroxyursolic Acid on NF-kappaB Activation Induced by TNF-alpha in Human Breast Cancer MCF-7 Cells.
Best Type (Red Delicious) Best Part (Apple Peelings):
Antioxidant and antiproliferative activities of selected New York apple cultivars.
Triterpenoids isolated from apple peels have potent antiproliferative activity and may be partially responsible for apple's anticancer activity.
Apple phytochemicals and their health benefits
Apple peels as a value-added food ingredient.