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Supplements, Research, AML Herbal Regimen


Peer reviewed journal papers preferred (PubMed) see: Google Scholar
Other Resources: NCCAM Clinical Trial Directory, Complimentary Medicine Search
Evidence Based CAM, Oregon State University, Sloan Kettering, Creighton University, NCCAM Herbs, HerbMed, Sigma-Aldrich


Apoptosis, Review, Epigenetics, ROS Therapy, Blood-Brain, Cell Paths, Synergisms
Delivery, Dose Logs, Disclaimer
Supplement Dosage Regimen (2 wk template designed July 2008)
      (Note from later: this was never implemented as such - see actual dose log)
This regimen (dosage and items) is still being designed for Jaymun a 33 pound 2 year old based on new evidence
and pending any other experimental hospital therapy offered to us by the doctors. At the very least it could provide hospital therapies with an extra edge, and on the other hand it may be all we have left (medically speaking)
to fight refractory, relapsed, congenintal AML, to extend Jaymun's life and ease symptoms.

See links to supplements on left - this regimen is not yet implemented because of unanswered questions (dangers?).
Also - sections of Jaymun's actual dosage log will replace parts of this plan.

Goals for Jaymun:
  To get the anti-LSC effect of FeverFew tea (parthenolide)
  To get the anti-blast effect of substances like (Green tea, Resveratrol, Pau d'Arco, Garlic, Quercetin, Ellagic Acid, etc.)
  To get the immune/NK boost of several other substances (Astragalus, Colostrum, Reishi Mushrooms, Echinacea, etc.)
  To strengthen/repair digestive system (Aloe, Slippery Elm, Burdock, Vitamin E, etc.)
  To build blood faster (Chorophyll, Spirulena, etc.)
  To heal/protect the nervous system/brain (GABA, Omega 3, etc.)
  To detox and support the liver/kidneys (Milk Thistle, Mangosteen, N Acytl Cysteine, etc.)
  To maximize synergistic anti-leukemic effects of Echinacea, Milk Thistle, Resveratrol, Mangosteen, Goji, Quercetin, Green Tea, Ellagic Acid, etc.)
(Note - still working on adding live links for the products below)
Sunday Monday Tuesday Wednesday Thursday Friday Saturday Sunday Monday Tuesday Wednesday Thursday Friday Saturday
Miscellaneous:        
  Water oz.     *2 oz *2 oz *2 oz *2 oz *2 oz *2 oz *2 oz *2 oz *2 oz *2 oz *2 oz *2 oz *2 oz *2 oz  
 
Digestive Healing / Prebiotics / Probiotics / Antacid:    
  Liquid Aloe Vera oz.   healing/soothing/prebiotic 2 oz 2 oz 2 oz 2 oz 2 oz 2 oz 2 oz 2 oz 2 oz 2 oz 2 oz 2 oz 2 oz 2 oz  
Slippery Elm capsule healing/soothing 2 2 2 2 2 2 2 2 2 2 2 2 2 2
  Glyco capsule (oligosaccharides)   prebiotic 2 2 2 2 2 2 2 2 2 2 2 2 2 2  
Vitamin E capsule healing 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5
# Bifidophilus   probiotic 1   1   1   1   1   1   1    
Kefir (raw from Grassway Farms) probiotic 4 oz 4 oz 4 oz 4 oz 4 oz 4 oz 4 oz 4 oz 4 oz 4 oz 4 oz 4 oz 4 oz 4 oz
  Natto (Bacillus subtilis natto) (Vit K2) probiotic        
 
Blood Nutrients / Regulation:      
  Liquid Chlorophyll oz.     2 oz 2 oz 2 oz 2 oz 2 oz 2 oz 2 oz 2 oz 2 oz 2 oz 2 oz 2 oz 2 oz 2 oz  
Barley capsule 1 1 1 1 1 1
  Spirulena capsule (Vit K1?)       1   1     1   1    
Alfalfa capsule 1 1   1 1
 
Immune System / Anti-Cancer:      
& Green Tea (capsule in tea mix) EGCG *.5 *.5 *.5 *.5 *.5 *.5 *.5 *.5 *.5 *.5 *.5 *.5 *.5 *.5
  Green Tea (capsule mixed) anti-platelet? EGCG 1   1 1   1 1     1 1   1  
Astragalus 1 1 1 1 1 1
& Una de Gato   anti-platelet?     *1 *1 *1     *1 *1 *1  
Immune Stimulator 1 1 1 1
  Trigger Immune (TCM)       *1 *1       *1 *1    
Colostrum 1 1 1 1   1 1 1 1
& Curcumin       1 1 1     1 1 1    
& Ho Shou Wu (capsule) anti-platelet? Quercetin *1 *1 *1  
  Citrus Bioflavonoids   Vit C / hesperedin / rutin     1 1 1   1 1  
SC Formula Shark Cart. 1   1 1 1
& Cholester-Reg II   Resveratrol   *1 *1 *1       *1 *1 *1    
& Vitamin K2 ??????  
& FeverFew ??????            
Celasterol ??????  
 
 
Nervous / Circulation:      
  Rose Hips   Vit C 1 1 1 1 1 1 1     1 1    
Omega 3 Omega 3 1 1 1 1 1 1 1 1
  Flaxseed Oil   Omega 3   1   1   1     1   1   1    
Vitamin K1 ????? clotting  
  Horsetail ?????   clotting (but diuretic?)        
 
Liver / Kidneys:        
  Milk Thistle (tablet crushed)   Silymarin 1   1 1 1     1 1  
N-Acytl Cysteine  
 
AntiOxident:        
  Thai-Go oz.   Mangosteen   1 oz 1 oz   1oz    
Noni oz. (potassium) Noni 1 oz 1 oz 1oz
  Odwalla Pomegrand oz.   Pomegranate         1oz 1oz 1oz  
Super AntiOxident capsule  
  Grapine (tablet crushed)       1 1   1 1     1 1      
Notes:        
  & Need to figure out theraputic dosage for these items?   Give extra doses of these items (warm tea where possible) spaced out during that day.    
# Mix the probiotics with milk, yogurt, or Kefir to administer
  * These items are first mixed with the preheated (mildly) water and after cooling the rest is mixed in - drawn into two ounce syringes, and given 2 to 4 ounces at a time (an hour apart if needed) through his NG tube    
I think Curcumin bothers Jaymun's stomach - so I combine curcumin dose with aloe vera for soothing, and Kefir so the grains are suspended and don't get stuck in his NG tube
  When making small two-ounce batches of concentrated tea - before administering, mix with 1 oz of liquid aloe vera to cool and sooth    



Challenges / Questions:
  FeverFew, Quercetin, etc. interfere with platelets (reduce clotting/increase risk of bleeding) (so extra Vitamin K?)
  FeverFew increases constipation? (so supplement Slippery Elm and "whole leaf" Aloe?)
  FeverFew depletes glutethione - (so supplement N-Acytl Cysteine?)
  Which items (FeverFew, Green Tea, Una de Gato, etc.) work in oxidative manner and does that have anything to do with antioxidents?
  (if so, should the rotation be longer (space out antioxidents) or should we shun things like N-Acytl Cysteine alltogether?)
  Sesquiterpines seem to have a Tachy side effect - Would premeding with Tylanol 1/2 hour before FeverFew help?
  Is Curcumin hard on Jaymun's stomach? - So give with aloe and food?
  Burdock sensitises cancer cells to a "nutritionally starved" condition - is that even possible here?
  After seven days Echinacea suppresses immune system? So one week on, two weeks off for Echinacea?
  Check out the Soy (Genestein)/Estrogen link before using that for Jaymun
  Burdock inhibits TNF-Alpha from activated Macrophages - how to best use with reishi mushrooms (that activate macrophages)